Semantic Farm and Bioregistry Updates - November 15th, 2026
This week saw the addition of 28 new records, update of 80 records, and addition of one new collection to the Semantic Farm and the Bioregistry, many motivated by the WikiPathways project and contributed by Javier Millán Acosta.
New Records
Of the 28 new records were added, several were follow-ups to last week’s updates on the Ontologies4Chem conference, including the addition of 17 records for components of PubChem’s RDF. The Semantic Farm/Bioregistry also received three external contributions:
- the Cleavage Atlas by Rens de Groot
- Digital Identity Optimization and Ontology of Digital Identity Reference Vocabulary by Daniel Beránek
- ChEMBL Assay by Javier Millán Acosta.
The Clinical Metadata Exploration Ontology (CMEO) was accepted in the OBO Foundry and was automatically added by the weekly update workflow.
| Prefix | Name |
|---|---|
| chembl.assay | ChEMBL assay |
| cleavageatlas | Cleavage Atlas |
| CMEO | Clinical Metadata Exploration Ontology |
| dio-odi | Digital Identity Optimization and Ontology of Digital Identity Reference Vocabulary |
| formats | File Formats |
| iochem | ioChem-BD Schema |
| math | Math Vocabulary |
| ofbo | Organic Flow Battery Ontology |
| ontoiochem | OntoIochem Core Ontology |
| pubchem.anatomy | PubChem anatomy |
| pubchem.author | PubChem author |
| pubchem.conserveddomain | PubChem conserved domain |
| pubchem.cooccurrence | PubChem co-occurrence |
| pubchem.descriptor | PubChem descriptor |
| pubchem.disease | PubChem disease |
| pubchem.endpoint | PubChem endpoint |
| pubchem.grant | PubChem grant |
| pubchem.journal | PubChem journal |
| pubchem.measuregroup | PubChem measure group |
| pubchem.nbr | PubChem neighbor |
| pubchem.organization | PubChem organization |
| pubchem.pathway | PubChem pathway |
| pubchem.protein | PubChem protein |
| pubchem.reference | PubChem reference |
| pubchem.source | PubChem source |
| pubchem.synonym | PubChem synonym |
| sabdab | Structural Antibody Database |
| stat | POSIX Statistics Operations |
Updated Records
This week, 80 records were updated as a combination of manual contributions and alignment with 30+ external registries.
A key highlight was the 11 improvements submitted by Javier Millán Acosta on behalf of the WikiPathways project that added additional providers to several resources for chemicals, reactions, proteins, and cells relevant for annotating pathways in WikiPathways that appear in its RDF and can be queried by SPARQL.
Of these, several included the addition of RDF URI format strings, which encode how a local unique identifier from a resource should be encoded as a URI in RDF, versus a regular URI format string, which is used for resolution to a human-readable webpage. Some of these additions were providers, which are third party URIs which can be used to get information about an entity. For example, Javier added the RDF URI format in PubChem for NCBI Taxonomy (ncbitaxon).
| Prefix | Name |
|---|---|
| asmo | Atomistic Simulation Methods Ontology |
| atc | Anatomical Therapeutic Chemical Classification System |
| bcio | The Behaviour Change Intervention Ontology |
| building | Building Ontology |
| cdco | Crystallographic Defect Core Ontology |
| CHEBI | Chemical Entities of Biological Interest |
| chembl.cell | ChEMBL database of bioactive drug-like small molecules - Cell lines section |
| chemspider | ChemSpider |
| CHMO | Chemical Methods Ontology |
| CHR | Chromosome Ontology |
| CiTO | Citation Typing Ontology |
| climoo.plastico | ClimOO - Plastic Ontology |
| climoo.sdc2 | ClimOO - Sustainable Development and Climate Ontology |
| dbpedia.property | DBPedia Property |
| EC | Enzyme Nomenclature |
| edam | EDAM Ontology |
| edm.fibo | Financial Industry Business Ontology |
| EFO | Experimental Factor Ontology |
| emmo | Elementary Multiperspective Material Ontology |
| EMRO | Emotion Response Ontology |
| ENVO | Environment Ontology |
| fabio | The FRBR-aligned Bibliographic Ontology |
| FLOPO | Flora Phenotype Ontology |
| geosparql | GeoSPARQL |
| geosparql.function | GeoSPARQL Function |
| geosparql.rule | GeoSPARQL Rule |
| google.patent | Google Patents |
| inchikey | InChIKey |
| iofcore | Industrial Ontology Foundry (IOF) Core Ontology |
| kpio | Key Performance Indicator ontology |
| lipidmaps | LIPID MAPS |
| m4i | Metadata4Ing |
| mathmoddb | MathModDB Ontology and Knowledge Graph for Mathematical Models |
| mirbase.mature | miRBase mature miRNA |
| MMO | Measurement method ontology |
| MOD | PSI-MOD Protein Modifications Ontology |
| MOLSIM | Molecular Simulation Ontology |
| MS | Mass spectrometry ontology |
| ncbibook | NCBI Bookshelf |
| NCBIGene | NCBI Gene |
| NCBITaxon | NCBI Taxonomy |
| oboe | The Extensible Observation Ontology |
| OEO | Open Energy Ontology |
| PATO | Phenotype And Trait Ontology |
| physh | Physics Subject Headings |
| pmdco | Platform Material Digital Core Ontology |
| pride | Proteomics Identification Database Ontology |
| prima | Provenance Information for Materials Science Ontology |
| pubchem.bioassay | PubChem bioassay |
| pubchem.cell | PubChem cell line |
| pubchem.classification | PubChem classification |
| pubchem.element | PubChem element |
| pubchem.substance | PubChem substance |
| pubchem.vocabulary | PubChem Vocabulary |
| pubmed | PubMed |
| rfam | RNA family database |
| rhea | Rhea reaction |
| RXNO | Name Reaction Ontology |
| scretf | ScerTF |
| SIO | Semanticscience Integrated Ontology |
| SLM | SwissLipid |
| sre.cpo | Chemical Process Ontology |
| sre.hlo | Higher Level Ontology |
| tib.io | Information Objects Ontology |
| tib.lis | Industrial Data Ontology |
| tib.mat | Material properties ontology |
| tib.mdo | Materials Design Ontology |
| tib.mt | Mobility Theme |
| time | Time Ontology in OWL |
| TTO | Teleost taxonomy ontology |
| UBERON | Uber Anatomy Ontology |
| uniprot | UniProt Protein |
| uniref | UniRef |
| UO | Units of measurement ontology |
| UPA | Unipathway |
| vcard | Virtual Contact File |
| voc4cat | A vocabulary for the catalysis disciplines |
| VT | Vertebrate trait ontology |
| XAO | Xenopus Anatomy Ontology |
| ZP | Zebrafish Phenotype Ontology |
New Collections
Finally, I implemented a workflow for constructing a Semantic Farm/Bioregistry collection from a SPARQL endpoint that encodes its prefix definitions using SHACL in #2205. I used this to construct a collection for WikiPathways (0000048) which reflects many of the additions and updates from this week. Javier also suggested I could apply this same workflow to Rhea, AOP Wiki, and other resources that make SPARQL endpoints available.